Chemical Synthesis

Polyamide Amino Acids trimers as TAR RNA ligands and anti-HIV agents

Organic Chemistry / Fluorescence Resonance Energy Transfer / Cell Culture / In Vitro / Virus / Amino Acids / Amino Acid Profile / Bioorganic and medicinal Chemistry / Amino Acid Sequence / Antiviral Activity / Chemical Synthesis / Ligands / Amino Acids / Amino Acid Profile / Bioorganic and medicinal Chemistry / Amino Acid Sequence / Antiviral Activity / Chemical Synthesis / Ligands

Polyamide Amino Acids trimers as TAR RNA ligands and anti-HIV agents

Organic Chemistry / Fluorescence Resonance Energy Transfer / Cell Culture / In Vitro / Virus / Amino Acids / Amino Acid Profile / Bioorganic and medicinal Chemistry / Amino Acid Sequence / Antiviral Activity / Chemical Synthesis / Ligands / Amino Acids / Amino Acid Profile / Bioorganic and medicinal Chemistry / Amino Acid Sequence / Antiviral Activity / Chemical Synthesis / Ligands

Polyamide Amino Acids trimers as TAR RNA ligands and anti-HIV agents

Organic Chemistry / Fluorescence Resonance Energy Transfer / Cell Culture / In Vitro / Virus / Amino Acids / Amino Acid Profile / Bioorganic and medicinal Chemistry / Amino Acid Sequence / Antiviral Activity / Chemical Synthesis / Ligands / Amino Acids / Amino Acid Profile / Bioorganic and medicinal Chemistry / Amino Acid Sequence / Antiviral Activity / Chemical Synthesis / Ligands

Polyamide Amino Acids trimers as TAR RNA ligands and anti-HIV agents

Organic Chemistry / Fluorescence Resonance Energy Transfer / Cell Culture / In Vitro / Virus / Amino Acids / Amino Acid Profile / Bioorganic and medicinal Chemistry / Amino Acid Sequence / Antiviral Activity / Chemical Synthesis / Ligands / Amino Acids / Amino Acid Profile / Bioorganic and medicinal Chemistry / Amino Acid Sequence / Antiviral Activity / Chemical Synthesis / Ligands

In vitro and in vivo profile of 5-[(4′-trifluoromethyl-biphenyl-2-carbonyl)-amino]-1H-indole-2-carboxylic acid benzylmethyl carbamoylamide (dirlotapide), a novel potent MTP inhibitor for obesity

Organic Chemistry / Medicinal Chemistry / Obesity / Pharmacokinetics / Pharmaceutical Chemistry / Dogs / Cell line / In Vitro / Humans / Models / Animals / Drug Design / Enzyme / Food intake / In Vivo / Rats / Rat / Carboxylic Acids / Molecular Conformation / Bioorganic and medicinal Chemistry / Hydrogen-Ion Concentration / Chemical Synthesis / Carbamates / Selectivity / Dogs / Cell line / In Vitro / Humans / Models / Animals / Drug Design / Enzyme / Food intake / In Vivo / Rats / Rat / Carboxylic Acids / Molecular Conformation / Bioorganic and medicinal Chemistry / Hydrogen-Ion Concentration / Chemical Synthesis / Carbamates / Selectivity

Enhancement of pharmacokinetic properties and in vivo efficacy of benzylidene ketal M2 muscarinic receptor antagonists via benzamide modification

Organic Chemistry / Pharmacokinetics / In Vitro / Humans / Animals / Drug Design / Acetylcholine / Bioavailability / Microdialysis / In Vivo / Rats / Rat / Cholinergic Receptor / Bioorganic and medicinal Chemistry / Structure activity Relationship / Muscarinic Receptor / Chemical Synthesis / Area Under Curve / Benzamides / Drug Design / Acetylcholine / Bioavailability / Microdialysis / In Vivo / Rats / Rat / Cholinergic Receptor / Bioorganic and medicinal Chemistry / Structure activity Relationship / Muscarinic Receptor / Chemical Synthesis / Area Under Curve / Benzamides

Novel fungicidal benzylsulfanyl-phenylguanidines

Organic Chemistry / Caenorhabditis elegans / Biofilm / Animals / Sulfides / Bacteria / Candida albicans / Staphylococcus epidermidis / Antifungal Agents / Biological activity / Guanidines / Chemical Synthesis / Bactericidal Activity / Molecular Structure / Minimal Bactericidal Concentration / Bacteria / Candida albicans / Staphylococcus epidermidis / Antifungal Agents / Biological activity / Guanidines / Chemical Synthesis / Bactericidal Activity / Molecular Structure / Minimal Bactericidal Concentration

Antimalarial in-vivo activity of bis(9-amino-6-chloro-2-methoxyacridines)

Pharmacy / Malaria / In Vitro / Toxicity / Mice / Pharmacology and Clinical pharmacy / Female / Animals / Antimalarials / Alkylation / Acylation / Biological activity / Chloroquine / Chemical Synthesis / Plasmodium berghei / Pharmacology and Clinical pharmacy / Female / Animals / Antimalarials / Alkylation / Acylation / Biological activity / Chloroquine / Chemical Synthesis / Plasmodium berghei

Novel fungicidal benzylsulfanyl-phenylguanidines

Organic Chemistry / Caenorhabditis elegans / Biofilm / Animals / Sulfides / Bacteria / Candida albicans / Staphylococcus epidermidis / Antifungal Agents / Biological activity / Guanidines / Chemical Synthesis / Bactericidal Activity / Molecular Structure / Minimal Bactericidal Concentration / Bacteria / Candida albicans / Staphylococcus epidermidis / Antifungal Agents / Biological activity / Guanidines / Chemical Synthesis / Bactericidal Activity / Molecular Structure / Minimal Bactericidal Concentration

Site-specific incorporation of non-natural residues into peptides: Effect of residue structure on suppression and translation efficiencies

Biochemistry / Organic Chemistry / Beta decay / Animals / Context Effect / Protein structure / Tetrahedron / Amino Acid Profile / Acylation / Rabbits / Amino Acid Sequence / Base Sequence / Chemical Synthesis / Site-directed Mutagenesis / Organic Compound / Nucleic Acid Conformation / Protein Biosynthesis / Biochemistry and cell biology / Organic Acid / Nucleic Acid / Protein structure / Tetrahedron / Amino Acid Profile / Acylation / Rabbits / Amino Acid Sequence / Base Sequence / Chemical Synthesis / Site-directed Mutagenesis / Organic Compound / Nucleic Acid Conformation / Protein Biosynthesis / Biochemistry and cell biology / Organic Acid / Nucleic Acid

Leflunomide analogues as potential antiinflammatory agents

Treatment / Inflammation / Mice / Animals / Male / Rats / Edema / Structure activity Relationship / Chemical Synthesis / Rats / Edema / Structure activity Relationship / Chemical Synthesis

Leflunomide Analogues as Potential Antiinflammatory Agents

Treatment / Inflammation / Mice / Animals / Male / Rats / Edema / Structure activity Relationship / Chemical Synthesis / Rats / Edema / Structure activity Relationship / Chemical Synthesis

Carbamoyloximes as novel non-competitive mGlu5 receptor antagonists

Organic Chemistry / In Vitro / Animals / Metabotropic Glutamate Receptors / Enzyme / Rats / Oximes / Substrate Specificity / Pyridines / Bioorganic and medicinal Chemistry / Affinity / Chemical Synthesis / Carbamates / Rats / Oximes / Substrate Specificity / Pyridines / Bioorganic and medicinal Chemistry / Affinity / Chemical Synthesis / Carbamates

TiO2/MgAl layered double hydroxides mechanical mixtures as efficient photocatalysts in phenol degradation

Materials Engineering / Condensed Matter Physics / Electron Microscopy / Ultrasound / Crystal structure / X ray diffraction / Chemical Synthesis / Sol Gel Method / Layered Double Hydroxide / X ray diffraction / Chemical Synthesis / Sol Gel Method / Layered Double Hydroxide

N -Phenyl-1,2,4-triazoline-3,5-dione (PTAD) as a Dienophilic Dinitrogen Equivalent: A Simple Synthesis of 3-Amino-1,2,4-benzotriazines from Arylcarbodiimides

Organic Chemistry / Chemical Synthesis / Amine

Chemical Incorporation of 1-Methyladenosine, Minor tRNA Component, into Oligonucleotides

Adenosine / Nucleic Acids / Chemical Synthesis / Biochemistry and cell biology

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